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The more that is discovered about the intricate organization of the nervous system, the more it seems remarkable that genes can successfully specify the development of that system. Human genes contain too little information even to specify which hemisphere of the brain each of a human's 10'' neurons should occupy, let alone the hundreds of connections that each neuron makes.For such reasons, we can assume that there must be an important random factor in neural development, and in particular, that errors must and do occur in the development of all normal brains.
The most vivid expression of such errors occurs in genetically identical (isogenic) organisms. Even when reared under the same conditions, isogenic organisms are rarely exact copies of one another, and their differences have revealed much about the random variations that result from an organism's limited supply of genetic information. In isogenic Daphniae, for example, even though the position, size, and branching pattern of each optic neuron are remarkably constant, there is some variability in connectivity, and the number of synapses varies greatly. This variability is probably the result of random scatter beyond the resolution of genetic control and is best termed "imprecision," since its converse, the degree of clustering about a mean, is conventionally, called "precision."
Imprecision should be distinguished from developmental mistakes: wrongly migrated neurons, incorrect connections, and the like. To use a computer analogy, minor, rounding-off errors occur universally and are analogous to imprecision, but occasionally a binary digit is incorrectly transmitted, perhaps ruining a calculation, and this incorrect transmission is analogous to a developmental mistake. Thus, imprecision is a form of inaccuracy inherent within the limits of design, but mistakes are forms of gross fallibility.
Both impression and gross fallibility can plausibly be blamed on the insufficiency of genetic information, since either could be reduced by adding more information. It is universally accepted among information theorists that codes and languages can be made mistake-resistant by incorporating redundancy. However, since the amount of space available in any information system is limited, increased redundancy results in decreased precision. For example, π when written incorrectly in English, "three point oen four two, "can be understood correctly even though a typographical error has occurred. More precision could be gained, however, if those 24 spaces were filled with Arabic numerals; then π could be expressed to 23 significant digits, although any error would significantly change the meaning. There exists a trade-off, the more precisely a system is specified, using a given limited amount of information, the greater the danger of gross mistakes. The overall scheme by which genetic information is rationed out in organisms, therefore, must involve a compromise between two conflicting priorities: precision and the avoidance of gross mistakes.
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[数学 ]【新版】冲分救命题 -11998
The integers a, b, and c are positive, and a>b>c. When a, b, and c are divided by 3, the remainders are 0, 1, and 1, respectively.
[数学 ]【新版】冲分救命题 -11997
For all positive even integers n. n* represents the product of all even integers from 2 to n, inclusive. For example, 12*=12×10×8×6×4×2. What is the greatest prime factor of 20*+22*?
[数学 ]【新版】冲分救命题 -11996
[数学 ]【新版】冲分救命题 -11995
[数学 ]【新版】冲分救命题 -11994
In a game, the cards in a certain deck are distributed to players one at a time until each player has the same number of cards and there are not enough cards left in the deck to distribute one more card to each player. The number of cards in the deck is between 60 and 100. If the cards in the deck are distributed o 5 players, 2 cards will be left in the deck. If the cards in the deck are distributed to 6 players, 4 cards will be left in the deck. If the cards in the deck are distributed to 7 players, how many cards will be left in the deck?
[数学 ]【新版】冲分救命题 -11993
Let a be the greatest integer such that is a factor of 1,500, and let b be the greatest integer such that is a factor of 33,333,333. Which of the following statements are true? Indicate all such statements.
[数学 ]【新版】冲分救命题 -11992
A set consists of all three-digit positive integers with the following properties.Each integer is of the form JKL,where J,K,and I are digits;all the digits are nonzero;and the two-digit integers JK and KL are each divisible by 9.How many integers are in the set?
[数学 ]【新版】冲分救命题 -11991
[数学 ]【新版】冲分救命题 -11990
The number of children in a certain family is a prime number less than 10. The number of boys in the family is greater than the number of girls, and the number of boys is a prime number. If at least 1 of the children in the family is a girl, which of the following could be the number of boys in the family?Indicate all such numbers.
[数学 ]【新版】冲分救命题 -11989
[数学 ]【新版】冲分救命题 -11988
x and y are integers.
[数学 ]【新版】冲分救命题 -11987
x and y are integers.
[数学 ]【新版】冲分救命题 -11986
a and b are distinct odd prime numbers.
[数学 ]【新版】冲分救命题 -11985
When the integer n is divided by 33, the remainder is 24. Which of the following must be a divisor of n?
[数学 ]【新版】冲分救命题 -11984
4.What is the length of an edge of the smallest solid cube that can be made by placing together solid rectangular blocks of size 7 by 6 by 3?
[数学 ]【新版】冲分救命题 -11983
Light travels at approximately 186,000 miles per second.Which of the following is closest to the number of miles that light travels in 3 hours.
[数学 ]【新版】冲分救命题 -11982
The number n is the least positive integer for which 108n is the square of an intege
[数学 ]【新版】冲分救命题 -11981
The number n is the least positive integer for which 108n is the square of an intege
[数学 ]【新版】冲分救命题 -11980
If x=2y+1, and y=2w, where w, x, and y are integers, which of the following must be an odd integer?
[数学 ]OG -11979
If x=2y+1, and y=2w, where w, x, and y are integers, which of the following must be an odd integer?
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